Effects of methyl prednisolone in early ARDS

Niacin Exacerbates Methyl Prednisolone-Induced Bone Changes in Growing Rats

Positive role of niacin on serum lipid profile of rats treated with glucocorticoids (GCs) has been reported. This study aims to evaluate effect of niacin on bone changes in GC-induced dyslipidemic rats. A number of 28 growing rats divided into four groups and treated as control, Methyl prednisolone (MP) group (3.5 mg/kg five days a week, SC); MPN group (MP + niacin 200 mg/kg/day orally) and MPA...

Steroids in Early ARDS.

2007;132;1094 Chest Jan G. Zijlstra and Jack J. Ligtenberg Steroids in Early ARDS http://chestjournal.chestpubs.org/content/132/3/1094.full.html and services can be found online on the World Wide Web at: The online version of this article, along with updated information ISSN:0012-3692 ) http://chestjournal.chestpubs.org/site/misc/reprints.xhtml ( of the copyright holder. may be reproduced or di...

Steroids in early ARDS?

Measurements and main results: There were 177 patients with ARDS (placebo, n = 92; corticosteroids, n = 85) including 129 (placebo, n = 67; corticosteroids, n = 62) nonresponders and 48 (placebo, n = 25; corticosteroids, n = 23) responders. In nonresponders, there were 50 deaths (75%) in the placebo group and 33 deaths (53%) in the steroid group (hazard ratio 0.57, 95% confidence interval 0.36-...

The Prophylactic Effect of Methyl Prednisolone Sodium Succinate against Fat Embolism in Long Bones Fractures

In this prospective study the effect of low dose methylprednisolone succinate (10mg/kg) on the incidence of fat embolism syndrome and isolated arterial hypoxemia in 99 patients with long bone fracture (52 control and 47 steroid-trated subjects) was studied. Frequency of fractures among the selected patients was as follows: femoral fracture 52.5%, tibial fracture 36.4%, both femoral and tibial f...

comparison of oral prednisolone pulse therapy with intravenous methyl prednisolone pulse therapy in severe alopecia areata